Journal article
Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta.
- Abstract:
-
Inhibitor of growth protein-2 (ING2) is a nuclear adaptor protein that can regulate p53 and histone acetylation in response to cellular stress and contains a PHD (plant homeodomain) finger that can interact with phosphatidylinositol-5-phosphate (PtdIns5P). However, whether or how nuclear PtdIns5P levels are regulated in response to cellular stress or whether ING2 can sense these changes has not been demonstrated. We show that UV irradiation increases nuclear PtdIns5P levels via inhibition of ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.molcel.2006.07.014
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Authors
Bibliographic Details
- Journal:
- Molecular cell
- Volume:
- 23
- Issue:
- 5
- Pages:
- 685-695
- Publication date:
- 2006-09-01
- DOI:
- EISSN:
-
1097-4164
- ISSN:
-
1097-2765
- Source identifiers:
-
384631
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:384631
- UUID:
-
uuid:0d8b1c6c-1f66-4cbb-ae42-da249364516d
- Local pid:
- pubs:384631
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2006
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