- Abstract:
-
Cerebral injury leading to brain death (BD) causes major physiologic derangements in potential organ donors, which may result in vascular-endothelial activation and affect posttransplant graft function. We investigated the kinetic of pro-coagulatory and pro-inflammatory endothelial activation and the subsequent oxidative stress and renal tubular injury, early after BD declaration. BD was induced by slowly inflating a balloon-catheter inserted in the extradural space over a period of 30 min. R...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1600-6143.2008.02166.x
-
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- Journal:
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
- Volume:
- 8
- Issue:
- 5
- Pages:
- 933-941
- Publication date:
- 2008-05-05
- DOI:
- EISSN:
-
1600-6143
- ISSN:
-
1600-6135
- URN:
-
uuid:0d7f850d-65f0-42fd-8225-dfb4fa48f871
- Source identifiers:
-
190842
- Local pid:
- pubs:190842
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
Early events in kidney donation: progression of endothelial activation, oxidative stress and tubular injury after brain death.
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