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Journal article

The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse.

Abstract:

Blimp1, a zinc-finger containing DNA-binding transcriptional repressor, functions as a master regulator of B cell terminal differentiation. Considerable evidence suggests that Blimp1 is required for the establishment of anteroposterior axis formation and the formation of head structures during early vertebrate development. In mouse embryos, Blimp1 is strongly expressed in axial mesendoderm, the tissue known to provide anterior patterning signals during gastrulation. Here, we describe for the ...

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Publication status:
Published

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Publisher copy:
10.1242/dev.01711

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Journal:
Development (Cambridge, England) More from this journal
Volume:
132
Issue:
6
Pages:
1315-1325
Publication date:
2005-03-01
DOI:
EISSN:
1477-9129
ISSN:
0950-1991
Language:
English
Keywords:
Pubs id:
pubs:16298
UUID:
uuid:0d63a752-3c69-4384-8eda-7f7c7189e12f
Local pid:
pubs:16298
Source identifiers:
16298
Deposit date:
2012-12-19

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