Journal article icon

Journal article

Synthesis of the enantiomers of 6-epicastanospermine and 1,6-diepicastanospermine from D- and L-gulonolactone.

Abstract:
The synthesis of the enantiomers of 6-epicastanospermine and of 1,6-diepicastanospermine from the enantiomeric gulonolactones is reported and the structure of the former is established as (1S,6R,7R,8R,8aR)-1,6,7,8-tetrahydroxyoctahydroindolizine. The inhibitory activities of the diastereomers against the amyloglucosidase-catalysed hydrolysis of p-nitrophenyl alpha-D-glucopyranoside were investigated, and the effects of 6-epicastanospermine and of 1,6-diepicastanospermine on 14 human liver glycosidases are reported.
Publication status:
Published

Actions


Access Document


Authors


Expand authors...
Journal:
Carbohydrate research
Volume:
205
Issue:
C
Pages:
269-282
Publication date:
1990-09-01
DOI:
EISSN:
1873-426X
ISSN:
0008-6215
Source identifiers:
43469
Language:
English
Keywords:
Pubs id:
pubs:43469
UUID:
uuid:0d5b431a-6897-47f4-9de6-4d5e542f6694
Local pid:
pubs:43469
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP