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Ventral hippocampal lesions affect anxiety but not spatial learning.

Abstract:

Rats with cytotoxic ventral hippocampal lesions which removed approximately 50% of the hippocampus (including dentate gyrus) starting from the temporal pole, displayed a reduction in freezing behaviour following the delivery of an unsignalled footshock in an operant chamber. This was more plausibly a result of reduced susceptibility to fear than a result of a lesion-induced increase in general motor activity. There was no consistent difference between sham and lesioned animals in spontaneous ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
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Journal:
Behavioural brain research
Volume:
139
Issue:
1-2
Pages:
197-213
Publication date:
2003-02-05
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
URN:
uuid:0d4faa1b-59dd-4edf-82a6-3570d98a9f78
Source identifiers:
10989
Local pid:
pubs:10989

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