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Modulation of bone morphogenetic protein-2 and bone morphogenetic protein-4 gene expression in osteoblastic cell lines.

Abstract:

Bone morphogenetic proteins (BMPs) belong to the transforming growth factor-beta (TGF-beta) superfamily and are crucial factors in the process of bone formation. Despite knowledge on their wide distribution and expression, however, there is very little information on the biological factors that affect gene transcription of these osteoinductive agents. To investigate this aspect of BMP gene regulation we have studied the effect of a number of factors known to affect osteogenic cells. Northern ...

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Publication status:
Published

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Authors


Oreffo, RO More by this author
Triffitt, JT More by this author
Journal:
Cellular and molecular biology (Noisy-le-Grand, France)
Volume:
44
Issue:
8
Pages:
1237-1246
Publication date:
1998-12-05
EISSN:
1165-158X
ISSN:
0145-5680
URN:
uuid:0d3a8361-aff2-4534-9a8c-1f473bd50584
Source identifiers:
108338
Local pid:
pubs:108338

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