Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function
BACKGROUND. Understanding the genetic architecture of cardiac structure and function may help to prevent and treat heart disease. This investigation sought to identify common genetic variations associated with inter-individual variability in cardiac structure and function.Expand abstract
METHODS. A GWAS meta-analysis of echocardiographic traits was performed, including 46,533 individuals from 30 studies (EchoGen consortium). The analysis included 16 traits of left ventricular (LV) structure, and ...
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- Peer reviewed
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- American Society for Clinical Investigation
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- Copyright © 2017 American Society for Clinical Investigation. Freely available online at [10.1172/JCI84840].
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