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Entorhinal cortex lesions disrupt the transition between the use of intra- and extramaze cues for navigation in the water maze.

Abstract:

This study with rats examined the effects of excitotoxic lesions to the entorhinal cortex (EC) and hippocampus (HPC) on using extramaze and intramaze cues to navigate to a hidden platform in a water maze. HPC lesions resulted in a disruption to the use of extramaze cues, but not intramaze cues, whereas EC lesions had no effect on the use of these cues when they were encountered for the first time. However, prior navigation training in which 1 type of cue was relevant disrupted navigation with...

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Publication status:
Published

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Publisher copy:
10.1037/0735-7044.117.3.588

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Journal:
Behavioral neuroscience
Volume:
117
Issue:
3
Pages:
588-595
Publication date:
2003-06-01
DOI:
EISSN:
1939-0084
ISSN:
0735-7044
Language:
English
Keywords:
Pubs id:
pubs:3901
UUID:
uuid:0d294c6a-5fea-4707-83f4-49ff82812bd7
Local pid:
pubs:3901
Source identifiers:
3901
Deposit date:
2012-12-19

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