- Abstract:
-
Cytotoxic T cells (CTL) recognize short peptide epitopes presented by class I glycoproteins encoded by the major histocompatibility complex (MHC). It is not yet known whether peptides containing posttranslationally modified amino acids can also be recognized by CTL. To address this issue, we have studied the immunogenicity and recognition of a glycopeptide carrying an O-linked N-acetylglucosamine (GlcNAc) monosaccharide-substituted serine residue. This posttranslational modification is cataly...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1084/jem.180.2.739
-
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- Journal:
- The Journal of experimental medicine
- Volume:
- 180
- Issue:
- 2
- Pages:
- 739-744
- Publication date:
- 1994-08-05
- DOI:
- EISSN:
-
1540-9538
- ISSN:
-
0022-1007
- URN:
-
uuid:0d03a882-be04-41d4-bf6c-4f44c070a60f
- Source identifiers:
-
35775
- Local pid:
- pubs:35775
- Copyright date:
- 1994
Journal article
Recognition of carbohydrate by major histocompatibility complex class I-restricted, glycopeptide-specific cytotoxic T lymphocytes.
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