Journal article icon

Journal article

The effect of anti-alpha4 integrin antibody on brain lesion activity in MS. The UK Antegren Study Group.

Abstract:

OBJECTIVE: To determine the effect of humanized monoclonal antibody against alpha4 integrin (reactive with alpha4beta1 integrin or very-late antigen-4) on MRI lesion activity in MS. METHODS: A randomized, double-blind, placebo-controlled trial in 72 patients with active relapsing-remitting and secondary progressive MS was performed. Each patient received two IV infusions of anti-alpha4 integrin antibody (natalizumab; Antegren) or placebo 4 weeks apart and was followed up for 24 weeks with ser...

Expand abstract

Actions


Authors


Tubridy, N More by this author
Capildeo, R More by this author
Chaudhuri, A More by this author
Expand authors...
Journal:
Neurology
Volume:
53
Issue:
3
Pages:
466-472
Publication date:
1999-08-11
ISSN:
0028-3878
URN:
uuid:0d01e46c-0c63-437a-8ac2-2a5d4db1a21f
Source identifiers:
387044
Local pid:
pubs:387044

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP