Journal article
The effect of anti-alpha4 integrin antibody on brain lesion activity in MS. The UK Antegren Study Group.
- Abstract:
-
OBJECTIVE: To determine the effect of humanized monoclonal antibody against alpha4 integrin (reactive with alpha4beta1 integrin or very-late antigen-4) on MRI lesion activity in MS. METHODS: A randomized, double-blind, placebo-controlled trial in 72 patients with active relapsing-remitting and secondary progressive MS was performed. Each patient received two IV infusions of anti-alpha4 integrin antibody (natalizumab; Antegren) or placebo 4 weeks apart and was followed up for 24 weeks with ser...
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Bibliographic Details
- Journal:
- Neurology
- Volume:
- 53
- Issue:
- 3
- Pages:
- 466-472
- Publication date:
- 1999-08-11
- ISSN:
-
0028-3878
- URN:
-
uuid:0d01e46c-0c63-437a-8ac2-2a5d4db1a21f
- Source identifiers:
-
387044
- Local pid:
- pubs:387044
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 1999
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