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Polymorphisms in Tumor Necrosis Factor and Other Cytokines As Risks for Infectious Diseases and the Septic Syndrome.

Abstract:

An increasing number of genetic association studies have implicated polymorphisms of cytokine genes as host genetic factors influencing susceptibility to infectious disease, primarily using a candidate gene approach based on knowledge of disease pathogenesis. The application and limitations of association studies are reviewed together with the impact of recent advances in single nucleotide polymorphism mapping on strategic approaches to defining genetic susceptibility loci. It often remains u...

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Publisher copy:
10.1007/s11908-007-1010-3

Authors


Journal:
Current infectious disease reports More from this journal
Volume:
3
Issue:
5
Pages:
427-439
Publication date:
2001-10-01
DOI:
EISSN:
1534-3146
ISSN:
1523-3847
Language:
English
Pubs id:
pubs:432831
UUID:
uuid:0cf50afb-faa4-4fff-b821-b5600e940112
Local pid:
pubs:432831
Source identifiers:
432831
Deposit date:
2013-11-17

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