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Kidney injury molecule-1 is an early noninvasive indicator for donor brain death-induced injury prior to kidney transplantation.

Abstract:

With more marginal deceased donors affecting graft viability, there is a need for specific parameters to assess kidney graft quality at the time of organ procurement in the deceased donor. Recently, kidney injury molecule-1 (Kim-1) was described as an early biomarker of renal proximal tubular damage. We assessed Kim-1 in a small animal brain death model as an early and noninvasive marker for donor-derived injury related to brain death and its sequelae, with subsequent confirmation in human do...

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Publication status:
Published

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Authors


Nijboer, WN More by this author
Schuurs, TA More by this author
van Goor, H More by this author
Vaidya, VS More by this author
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Journal:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Volume:
9
Issue:
8
Pages:
1752-1759
Publication date:
2009-08-05
DOI:
EISSN:
1600-6143
ISSN:
1600-6135
URN:
uuid:0ccca478-0914-466c-ae5c-b844d84095c0
Source identifiers:
190938
Local pid:
pubs:190938

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