Journal article
Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.
- Abstract:
-
Bacteria expressing type III secretion systems (T3SS) have been responsible for the deaths of millions worldwide, acting as key virulence elements in diseases ranging from plague to typhoid fever. The T3SS is composed of a basal body, which traverses both bacterial membranes, and an external needle through which effector proteins are secreted. We report multiple crystal structures of two proteins that sit at the tip of the needle and are essential for virulence: IpaD from Shigella flexneri an...
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- Publication status:
- Published
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- Publisher copy:
- 10.1074/jbc.m607945200
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Authors
Bibliographic Details
- Journal:
- Journal of biological chemistry
- Volume:
- 282
- Issue:
- 6
- Pages:
- 4035-4044
- Publication date:
- 2007-02-01
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- Source identifiers:
-
18279
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:18279
- UUID:
-
uuid:0cbb19e6-73f0-4583-8259-360b7fbdb128
- Local pid:
- pubs:18279
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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