Higher adherence to the EAT-Lancet reference diet is inversely associated with mortality in a UK population of cancer survivors

Journal article

Background: Significant advancements in treatment and care, as well as early detection, have contributed to an increase in cancer survival rates. Recently, the EAT-Lancet Commission on Food, Planet, Health proposed the “planetary health diet” but to date, no study has investigated the potential associations between adherence to the EAT-Lancet reference diet and mortality in cancer survivors. To determine whether higher adherence to the EAT-Lancet reference diet is associated with lower risk for all-cause, cancer, and cardiovascular mortality in cancer survivors. Methods: Data from the prospective UK Biobank study were used. Information from UK Biobank’s Touchscreen questionnaire was used to develop a score reflecting adherence to the EAT-Lancet reference diet. Cox proportional hazards regression was used to assess the association of the EAT-Lancet reference diet score with all-cause, cancer, and cardiovascular mortality in cancer survivors. Results: Within 25,348 cancer survivors, better adherence to the EAT-Lancet reference diet was inversely related to all-cause mortality (hazard ratio (HR): 0.97, 95% confidence interval (CI): 0.95–0.99), 1 unit increase) and cancer mortality (HR: 0.98, 95% CI: 0.96–1.00), while mostly null associations were observed for major cardiovascular mortality (HR: 0.99, 95% CI: 0.95–1.03). Conclusions: Our findings suggest the adoption of the EAT-Lancet reference diet is associated with lower all-cause and cancer-specific mortality among cancer survivors.

Authors: Karavasiloglou, N; Thompson, AS; Pestoni, G; Suter, F; Papier, K

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: BioMed Central
• Journal: BMC Medicine
• Volume: 23
• Issue: 1
• Article number: 286
• Publication date: 2025-05-13
• Acceptance date: 2025-04-28
• DOI: 10.1186/s12916-025-04106-x
• EISSN: 1741-7015
• Language: English
• Keywords: Diet; Mortality; EAT-Lancet; Survivors; Cancer; Sustainable