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A role for GATA5 in Xenopus endoderm specification.

Abstract:

The endoderm gives rise to the gut and tissues that develop as outgrowths of the gut tube, including the lungs, liver and pancreas. Here we show that GATA5, a zinc-finger transcription factor, is expressed in the yolk-rich vegetal cells of Xenopus embryos from the early gastrula stage onwards, when these cells become committed to form endoderm. At mid-gastrula stages, GATA5 is restricted to the sub-blastoporal endoderm and is the first molecular marker for this subset of endodermal cells so f...

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Journal:
Development (Cambridge, England)
Volume:
127
Issue:
20
Pages:
4345-4360
Publication date:
2000-10-05
EISSN:
1477-9129
ISSN:
0950-1991
URN:
uuid:0c998199-bb35-41b9-b67a-48b71a42b29f
Source identifiers:
106874
Local pid:
pubs:106874

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