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Other 4-methanolquinolines, amyl alcohols and phentathrenes: Mefloquine, lumefantrine and halofantrine

Abstract:

This chapter describes mefloquine, pyronaridine, halofantrine, piperaquine and lumefantrine under the broader title of the 4-methanolquinolines, amyl alcohols and phentathrenes. We provide a brief resume of each drug, in terms of their chemical properties, formulae, pharmacokinetics, clinical indications for use, and their efficacy and safety. Recognizing the limited number of antimalarials available, and in the developmental pipeline, attention is focussed on describing the history of each d...

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Publisher copy:
10.1007/978-3-0346-0480-2_5

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Journal:
Milestones in Drug Therapy
Volume:
41
Pages:
95-111
Publication date:
2012-01-01
DOI:
URN:
uuid:0c7bb67e-0f3d-4d69-a708-1e31791b2d38
Source identifiers:
354615
Local pid:
pubs:354615
Language:
English

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