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Journal article

Proteins modulation in human skeletal muscle in the early phase of adaptation to hypobaric hypoxia.

Abstract:

High altitude hypoxia is a paraphysiological condition triggering redox status disturbances of cell organization leading, via oxidative stress, to proteins, lipids, and DNA damage. In man, skeletal muscle, after prolonged exposure to hypoxia, undergoes mass reduction and alterations at the cellular level featuring a reduction of mitochondrial volume density, accumulation of lipofuscin, a product of lipid peroxidation, and dysregulation of enzymes whose time course is unknown. The effects of 7...

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Publication status:
Published

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Publisher copy:
10.1002/pmic.200800232

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Journal:
Proteomics
Volume:
8
Issue:
22
Pages:
4668-4679
Publication date:
2008-11-05
DOI:
EISSN:
1615-9861
ISSN:
1615-9853
URN:
uuid:0c7aaf16-64f3-4e32-8b3b-68b217772f39
Source identifiers:
229253
Local pid:
pubs:229253

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