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Journal article

Interferon lambda: opportunities, risks, and uncertainties in the fight against HCV

Abstract:

Innate immunity is key to the fight against the daily onslaught from viruses that our bodies are subjected to. Essential to this response are the interferons (IFNs) that prime our cells to block viral pathogens. Recent evidence suggests that theType III (l) IFNs are intimately associated with the immune response to hepatitis C virus (HCV) infection. Genome-wide association studies have identified polymorphisms within the IFN-l gene locus that correlate with response to IFNa-based antiviral th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fimmu.2014.00545

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Publisher:
Frontiers Media
Journal:
Frontiers in Immunology More from this journal
Volume:
5
Pages:
545
Publication date:
2014-10-31
Acceptance date:
2014-10-13
DOI:
EISSN:
1664-3224
Language:
English
Keywords:
UUID:
uuid:0c778a0c-f8ca-4528-bdd4-d11daac1bd76
Local pid:
pubs:490899
Source identifiers:
490899
Deposit date:
2014-12-02

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