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Journal article

The influence of EDTA and citrate anticoagulant addition to human plasma on information recovery from NMR-based metabolic profiling studies.

Abstract:

The widely-used blood anticoagulants citrate and EDTA give rise to prominent peaks in (1)H NMR spectra of plasma samples collected in epidemiological and clinical studies, and these cause varying levels of interference in recovering biochemical information on endogenous metabolites. To investigate both the potential metabolic information loss caused by these substances and any possible inter-molecular interactions between the anticoagulants and endogenous components, the (1)H NMR spectra of 4...

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Publication status:
Published

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Publisher copy:
10.1039/b907021d

Authors


Journal:
Molecular bioSystems
Volume:
6
Issue:
1
Pages:
215-224
Publication date:
2010-01-01
DOI:
EISSN:
1742-2051
ISSN:
1742-206X
Language:
English
Keywords:
Pubs id:
pubs:49340
UUID:
uuid:0c774d51-853d-4002-8464-1e36d6b018f3
Local pid:
pubs:49340
Source identifiers:
49340
Deposit date:
2012-12-19

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