Is fresh-frozen plasma clinically effective? An update of a systematic review of randomized controlled trials.

Journal article

The clinical use of frozen plasma (FP) continues to increase, both in prophylactic and in therapeutic settings. In 2004, a systematic review of all published randomized controlled trials (RCTs) revealed a lack of evidence that supported the efficacy of FP use. This is an update that includes all new RCTs published since the original review.

Authors: Yang, L; Stanworth, S; Hopewell, S; Doree, C; Murphy, M

• Journal: Transfusion
• Volume: 52
• Issue: 8
• Pages: 1673-1686
• Publication date: 2012-08-01
• DOI: 10.1111/j.1537-2995.2011.03515.x
• EISSN: 1537-2995
• ISSN: 0007-1048
• Language: English
• Keywords: Plasma; Liver Diseases; Humans; Hematologic Diseases; Education, Medical, Continuing; Randomized Controlled Trials as Topic; Heart Diseases; Evidence-Based Medicine; Blood Component Transfusion