Anti-androgen treatment in women with acne: a controlled trial.

Journal article

Ninety female patients with acne were allocated randomly to one of three groups and treated either with Diane, a high dose cyproterone acetate (CPA) regime with ethinyloestradiol, or Minovlar. The same dose of oestrogen was common to all three treatment groups. Patients were assessed every 2 months for 6 months, by grading for severity of the acne, lesion counts and photography, and subjectively using a visual analogue scale. In addition, bacteriological sampling and sebum excretion rate (SER...

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Authors: Miller, J; Wojnarowska, F; Dowd, P; Ashton, R; O'Brien, T

• Publication status: Published
• Journal: British journal of dermatology
• Volume: 114
• Issue: 6
• Pages: 705-716
• Publication date: 1986-06-01
• DOI: 10.1111/j.1365-2133.1986.tb04880.x
• EISSN: 1365-2133
• ISSN: 0007-0963
• Language: English
• Keywords: Female; Humans; Adolescent; Drug Combinations; Cyproterone Acetate; Random Allocation; Ethinyl Estradiol; Cyproterone; Norethindrone; Androgen Antagonists; Clinical Trials as Topic; Acne Vulgaris; Double-Blind Method; Drug Therapy, Combination; Adult