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Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase.

Abstract:

The Phycomyces blakesleeanus wild-type is yellow, because it accumulates beta-carotene as the main carotenoid. A new carotenoid mutant of this fungus (A486) was isolated, after treatment with ethyl methane sulfonate (EMS), showing a whitish coloration. It accumulates large amounts of phytoene, small quantities of phytofluene, zeta-carotene and neurosporene, in decreasing amounts, and traces of beta-carotene. This phenotype indicates that it carries a leaky mutation affecting the enzyme phytoe...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
European journal of biochemistry / FEBS More from this journal
Volume:
269
Issue:
3
Pages:
902-908
Publication date:
2002-02-01
DOI:
EISSN:
1432-1033
ISSN:
0014-2956
Language:
English
Keywords:
Pubs id:
pubs:354445
UUID:
uuid:0c62914e-ac7c-44a3-bc63-96ce2fe4df77
Local pid:
pubs:354445
Source identifiers:
354445
Deposit date:
2013-11-17

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