Assessing potential errors of MRI-based measurements of pulmonary blood flow using a detailed network flow model.

Journal article

MRI images of pulmonary blood flow using arterial spin labeling (ASL) measure the delivery of magnetically tagged blood to an image plane during one systolic ejection period. However, the method potentially suffers from two problems, each of which may depend on the imaging plane location: 1) the inversion plane is thicker than the imaging plane, resulting in a gap that blood must cross to be detected in the image; and 2) ASL includes signal contributions from tagged blood in conduit vessels (...

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Authors: Burrowes, K; Buxton, R; Prisk, G

• Publication status: Published
• Journal: Journal of applied physiology (Bethesda, Md. : 1985)
• Volume: 113
• Issue: 1
• Pages: 130-141
• Publication date: 2012-07-01
• DOI: 10.1152/japplphysiol.00894.2011
• EISSN: 1522-1601
• ISSN: 8750-7587
• Language: English
• Keywords: Adult; Pulmonary Circulation; Magnetic Resonance Imaging; Male; Arteries; Spin Labels; Reproducibility of Results; Models, Biological; Computer Simulation; Humans; Lung