- Abstract:
-
Virus-like particles (VLPs) consist of one or more viral coat proteins that assemble into particles. They can be taken up by antigen presenting cells (APC), peptides derived from them are presented on MHC class I molecules at the cell surface, and thereby prime a CD8+ T cell response, either against the particle-forming protein itself (such as Hepatitis B surface antigen) or additional peptide sequences that are produced as fusions with the particle-forming protein. This article describes the...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1385/mb:19:2:169
-
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- Journal:
- Molecular biotechnology
- Volume:
- 19
- Issue:
- 2
- Pages:
- 169-177
- Publication date:
- 2001-10-05
- DOI:
- EISSN:
-
1559-0305
- ISSN:
-
1073-6085
- URN:
-
uuid:0c622d15-1c0c-4d54-897b-1bade22f76f1
- Source identifiers:
-
32003
- Local pid:
- pubs:32003
- Language:
- English
- Keywords:
- Copyright date:
- 2001
Journal article
Virus-like particles as vaccine adjuvants.
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