Journal article icon

Journal article

Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E.

Abstract:

HLA-E is the first human class Ib major histocompatibility complex molecule to be crystallized. HLA-E is highly conserved and almost nonpolymorphic, and has recently been shown to be the first specialized ligand for natural killer cell receptors. In functional studies, HLA-E is unlike the class Ia MHC molecules in having tightly restricted peptide binding specificity. HLA-E binds a limited set of almost identical leader sequence peptides derived from class Ia molecules and presents these at t...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/pro.5560070525

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
CCMP
Role:
Author
Expand authors...
Journal:
Protein science : a publication of the Protein Society
Volume:
7
Issue:
5
Pages:
1264-1266
Publication date:
1998-05-01
DOI:
EISSN:
1469-896X
ISSN:
0961-8368
Source identifiers:
9665
Language:
English
Keywords:
Pubs id:
pubs:9665
UUID:
uuid:0c5bcdc6-11bf-42e2-9ec9-613b82df25cc
Local pid:
pubs:9665
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP