Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E.

O'Callaghan, CA; Tormo, J; Willcox, BE; Blundell, CD; Jakobsen, BK; Stuart, DI; Mcmichael, AJ; Bell, JI; Jones, EY

Abstract:

HLA-E is the first human class Ib major histocompatibility complex molecule to be crystallized. HLA-E is highly conserved and almost nonpolymorphic, and has recently been shown to be the first specialized ligand for natural killer cell receptors. In functional studies, HLA-E is unlike the class Ia MHC molecules in having tightly restricted peptide binding specificity. HLA-E binds a limited set of almost identical leader sequence peptides derived from class Ia molecules and presents these at t...

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APA Style

O'Callaghan, C. A., Tormo, J., Willcox, B. E., Blundell, C. D., Jakobsen, B. K., Stuart, D. I., Mcmichael, A. J., Bell, J. I., & Jones, E. Y. (1998). Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E. Protein Science : a Publication of the Protein Society, 7(5), 1264–1266.

MLA Style

O'Callaghan, C. A., et al. “Production, Crystallization, and Preliminary X-Ray Analysis of the Human MHC Class Ib Molecule HLA-E.” Protein Science : a Publication of the Protein Society, vol. 7, no. 5, Protein science : a publication of the Protein Society, 1998, pp. 1264–66.

Chicago Style

O'Callaghan, CA, J Tormo, BE Willcox, CD Blundell, BK Jakobsen, DI Stuart, AJ Mcmichael, JI Bell, and EY Jones. 1998. “Production, Crystallization, and Preliminary X-Ray Analysis of the Human MHC Class Ib Molecule HLA-E.” Protein Science : a Publication of the Protein Society 7 (5): 1264–66.
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