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A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.

Abstract:: Renal cell carcinoma (RCC) is the most lethal urologic cancer. Only two common susceptibility loci for RCC have been confirmed to date. To identify additional RCC common susceptibility loci, we conducted an independent genome-wide association study (GWAS). We analyzed 533 191 single nucleotide polymorphisms (SNPs) for association with RCC in 894 cases and 1516 controls of European descent recruited from MD Anderson Cancer Center in the primary scan, and validated the top 500 SNPs in silico in...
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Publication status:: Published

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APA Style

Wu, X., Scelo, G., Purdue, M., Rothman, N., Johansson, M., Ye, Y., Wang, Z., Zelenika, D., Moore, L., Wood, C., Prokhortchouk, E., Gaborieau, V., Jacobs, K., Chow, W., Toro, J. R., Zaridze, D., Lin, J., Lubinski, J., Trubicka, J., … Jinga, V. (2012). A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23. Human Molecular Genetics, 21(2), 456–462.

MLA Style

Wu, X., et al. “A Genome-Wide Association Study Identifies a Novel Susceptibility Locus for Renal Cell Carcinoma on 12p11.23.” Human Molecular Genetics, vol. 21, no. 2, 2012, pp. 456–62.

Chicago Style

Wu, X, G Scelo, M Purdue, N Rothman, M Johansson, Y Ye, Z Wang, et al. 2012. “A Genome-Wide Association Study Identifies a Novel Susceptibility Locus for Renal Cell Carcinoma on 12p11.23.” Human Molecular Genetics 21 (2): 456–62.
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Publisher copy:: 10.1093/hmg/ddr479

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+ Wu, X More by this author

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+ Scelo, G More by this author

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+ Purdue, M More by this author

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+ Rothman, N More by this author

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+ Johansson, M More by this author

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Bibliographic Details

Journal:: Human molecular genetics
Volume:: 21
Issue:: 2
Pages:: 456-462
Publication date:: 2012-01-01
DOI:: 10.1093/hmg/ddr479
EISSN:: 1460-2083
ISSN:: 0964-6906

Item Description

Language:: English
Keywords:: Genome-Wide Association Study

Chromosomes, Human, Pair 12

Carcinoma, Renal Cell

Humans

Genetic Predisposition to Disease

Kidney Neoplasms
Pubs id:: pubs:245979
UUID:: uuid:0c5941e3-c2e0-437d-844d-029078069373
Local pid:: pubs:245979
Source identifiers:: 245979
Deposit date:: 2012-12-19

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Copyright date:: 2012

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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