Journal article

Lack of modulation of the adrenocortical response to ACTH by an opioid peptide.

Abstract:: Eight normal male subjects received 1 mg dexamethasone at 23.00 h and 0.5 mg on wakening followed by a physiological intravenous dose of synthetic ACTH1-24 250 ng, with and without the administration of a stable met-enkephalin analogue (guanyl-DAMME, 100 micrograms) 10 minutes prior to the ACTH. The opioid analogue caused no change in the peak, incremental, or incremental area under the curve responses of plasma cortisol to the ACTH. This study does not support a role for opioid peptides in the acute modulation of the adreno-cortical response to ACTH.

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Howlett, T., Grossman, A., Froud, A., Perry, L., & Besser, G. (1991). Lack of modulation of the adrenocortical response to ACTH by an opioid peptide. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, 23(7), 341–343.

MLA Style

Howlett, T, et al. “Lack of Modulation of the Adrenocortical Response to ACTH by an Opioid Peptide.” Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, vol. 23, no. 7, 1991, pp. 341–43.

Chicago Style

Howlett, T, A Grossman, A Froud, L Perry, and G Besser. 1991. “Lack of Modulation of the Adrenocortical Response to ACTH by an Opioid Peptide.” Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme 23 (7): 341–43.
Print

Access Document

Publisher copy:: 10.1055/s-2007-1003692

Authors

+ Howlett, T More by this author

Role:: Author

+ Grossman, A More by this author

Institution:: University of Oxford
Division:: MSD
Department:: RDM
Sub department:: OCDEM
Role:: Author

+ Froud, A More by this author

Role:: Author

+ Perry, L More by this author

Role:: Author

+ Besser, G More by this author

Role:: Author

Journal:: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme More from this journal
Volume:: 23
Issue:: 7
Pages:: 341-343
Publication date:: 1991-07-01
DOI:: 10.1055/s-2007-1003692
EISSN:: 1439-4286
ISSN:: 0018-5043

Language:: English
Keywords:: Male

Adrenal Cortex

Adult

Humans

Hydrocortisone

D-Ala(2),MePhe(4),Met(0)-ol-enkephalin

Adrenocorticotropic Hormone

Prolactin
Pubs id:: pubs:138446
UUID:: uuid:0c57eefe-80ae-470e-a517-bb0a455723ed
Local pid:: pubs:138446
Source identifiers:: 138446
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_0c57eefe80ae470ea517bb0a455723ed

Terms of use

Copyright date:: 1991

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP