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In vitro studies on H-2-linked unresponsiveness to synthetic polypeptides. III. Production of an antigen-specific T helper cell factor to (T,G)-A--L.

Abstract:
The in vitro production, assay and partial characterization of an extremely potent antigen-specific T helper cell factor to poly-L-(Tyr, Glu)-poly-DL-Ala--poly-L-Lys [(T,G)-A--L] which may be an important physiological mediator of T cell function in vivo is described. The factor has an antigen-binding site, Ia and Ig-like determinants on the same molecular complex. The response to (T, G)-A--L is under H-2-linked Ir gene control, some but not all low responder haplotypes will produce the factor.
Publication status:
Published

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Publisher copy:
10.1002/eji.1830070703

Authors


Journal:
European journal of immunology
Volume:
7
Issue:
7
Pages:
417-421
Publication date:
1977-07-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:0c4b1091-551e-45a0-837a-3ba68c69e653
Source identifiers:
481872
Local pid:
pubs:481872

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