Journal article
Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes.
- Abstract:
-
During female meiosis, bivalent chromosomes are thought to be held together from birth until ovulation by sister chromatid cohesion mediated by cohesin complexes whose ring structure depends on kleisin subunits, either Rec8 or Scc1. Because cohesion is established at DNA replication in the embryo, its maintenance for such a long time may require cohesin turnover. To address whether Rec8- or Scc1-containing cohesin holds bivalents together and whether it turns over, we created mice whose kleis...
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- Publication status:
- Published
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- Publisher copy:
- 10.1101/gad.605910
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Bibliographic Details
- Journal:
- Genes and development
- Volume:
- 24
- Issue:
- 22
- Pages:
- 2505-2516
- Publication date:
- 2010-11-05
- DOI:
- EISSN:
-
1549-5477
- ISSN:
-
0890-9369
- URN:
-
uuid:0c49efd4-2687-44c8-b741-683405558e0d
- Source identifiers:
-
98385
- Local pid:
- pubs:98385
Item Description
Terms of use
- Copyright date:
- 2010
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