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Journal article

Selection of apoptotic cell specific human antibodies from adult bone marrow

Abstract:

Autoreactive antibodies that recognize neo-determinants on apoptotic cells in mice have been proposed to have protective, homeostatic and immunoregulatory properties, although our knowledge about the equivalent antibodies in humans has been much more limited. In the current study, human monoclonal antibodies with binding specificity for apoptotic cells were isolated from the bone marrow of healthy adults using phage display technology. These antibodies were shown to recognize phosphorylcholin...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0095999

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
9
Issue:
4
Pages:
e95999
Publication date:
2014-04-23
Acceptance date:
2014-04-02
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
UUID:
uuid:0c39fe3d-bf2f-49a3-9845-587db1339b86
Local pid:
pubs:464472
Source identifiers:
464472
Deposit date:
2014-06-17

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