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Fixing the model for transcription: the DNA moves, not the polymerase.

Abstract:
The traditional model for transcription sees active polymerases tracking along their templates. An alternative (controversial) model has active enzymes immobilized in "factories." Recent evidence supports the idea that the DNA moves, not the polymerase, and points to alternative explanations of how regulatory motifs like enhancers and silencers work.

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Publisher copy:
10.4161/trns.2.1.14275

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Transcription More from this journal
Volume:
2
Issue:
1
Pages:
41-44
Publication date:
2011-01-01
DOI:
EISSN:
2154-1272
ISSN:
2154-1264
Language:
English
Keywords:
Pubs id:
pubs:118077
UUID:
uuid:0c3963e7-372f-4adc-8964-510a61471cc4
Local pid:
pubs:118077
Source identifiers:
118077
Deposit date:
2012-12-19

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