Serial autofluorescence imaging over two years following indocyanine green-assisted internal limiting membrane peel for macular hole.

Journal article

A 65-year-old patient with an idiopathic full-thickness macular hole underwent a vitrectomy, inner limiting membrane (ILM) peel and gas tamponade. The ILM was stained using 0.5% indocyanine green (ICG). Postoperative autofluorescence imaging shows a central focal hyperfluorescence surrounded by a perifoveal hypofluoresecnt area corresponding to the dyed and peeled ILM. Serial autofluorescence images showed progressive decrease in staining until 2 years later when no signs of ICG autofluorescence were apparent. The visual acuity for this patient improved two Snellen lines from 6/36 to 6/18 at 2 years. ICG may not be clinically toxic as is currently feared.

Authors: Kersey, T; Bolton, A; Patel, C

• Publication status: Published
• Journal: Clinical and experimental ophthalmology
• Volume: 33
• Issue: 5
• Pages: 538-539
• Publication date: 2005-10-01
• DOI: 10.1111/j.1442-9071.2005.01078.x
• EISSN: 1442-9071
• ISSN: 1442-6404
• Language: English
• Keywords: Vitrectomy; Fluorescence; Sulfur Hexafluoride; Diagnostic Imaging; Tomography, Optical Coherence; Female; Humans; Follow-Up Studies; Basement Membrane; Aged; Coloring Agents; Indocyanine Green; Prone Position; Retinal Perforations