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Journal article

Behavior of mesenchymal stem cells in the chemical microenvironment of the intervertebral disc.

Abstract:

STUDY DESIGN: Responses of mesenchymal stem cells (MSCs) from 2 age groups was analyzed under chemical conditions representative of the intervertebral disc (IVD) (low glucose levels, acidic pH, high osmolarity, and combined conditions). OBJECTIVE.: To determine the microenvironmental conditions of the IVD that are critical for MSC-based tissue repair and to determine whether MSCs from different age groups respond differently. SUMMARY OF BACKGROUND DATA: MSCs offer promise for IVD repair, but ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Spine
Volume:
33
Issue:
17
Pages:
1843-1849
Publication date:
2008-08-01
DOI:
EISSN:
1528-1159
ISSN:
0362-2436
Source identifiers:
239085
Language:
English
Keywords:
Pubs id:
pubs:239085
UUID:
uuid:0c2a5907-9740-4e4a-8168-1e58debe1659
Local pid:
pubs:239085
Deposit date:
2012-12-19

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