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Roles for cytoplasmic polyadenylation in cell cycle regulation.

Abstract:

Polyadenylation of eukaryotic mRNAs in the nucleus promotes their translation following export to the cytoplasm and is an important determinant of mRNA stability. An additional level of control of gene expression is provided by cytoplasmic polyadenylation, which activates translation of a number of mRNAs important in orchestrating cell cycle events in oocytes. Recent studies indicate that cytoplasmic polyadenylation may be a mechanism of translational activation that is more widespread in euk...

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Publication status:
Published

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Publisher copy:
10.1002/jcb.10300

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Journal of cellular biochemistry More from this journal
Volume:
87
Issue:
3
Pages:
258-265
Publication date:
2002-01-01
DOI:
EISSN:
1097-4644
ISSN:
0730-2312
Language:
English
Keywords:
Pubs id:
pubs:9240
UUID:
uuid:0c29b576-13c3-4829-8d27-fefe397b7d36
Local pid:
pubs:9240
Source identifiers:
9240
Deposit date:
2012-12-19

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