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Changes in peripheral chemoreflex sensitivity during sustained, isocapnic hypoxia.

Abstract:

One hypothesis concerning the origin of hypoxic ventilatory decline is that hypoxia acts centrally to depress peripheral chemoreflex loop activity. To investigate possible changes in peripheral chemoreflex loop activity during sustained, isocapnic hypoxia, the ventilatory responses to four one minute pulses of either extra hypoxia (45 Torr) or carbon dioxide (8 Torr above resting levels) were measured in man at minutes 2, 7, 12, and 17 of a 23 min isocapnic, hypoxic period (50 Torr). For hypo...

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Respiration physiology
Volume:
82
Issue:
2
Pages:
161-176
Publication date:
1990-11-01
DOI:
ISSN:
0034-5687
Source identifiers:
114094
Language:
English
Keywords:
Pubs id:
pubs:114094
UUID:
uuid:0c146cf9-4f10-448c-aa5d-eeafed1fe31c
Local pid:
pubs:114094
Deposit date:
2013-11-17

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