Synaptic potentiation and sleep need: clues from molecular and electrophysiological studies.
Sleep is homeostatically regulated in all species that have been carefully studied. In mammals and birds, the best characterized marker of sleep pressure is slow wave activity (SWA), defined as the electroencephalogram (EEG) power between 0.5 and 4 Hz during NREM sleep. SWA peaks at sleep onset and decreases with time spent asleep, and reflects the synchronous firing of cortical neurons coordinated by an underlying slow oscillation, the fundamental cellular phenomenon of NREM sleep. We have r...Expand abstract
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