The robotic mouse: unravelling the function of AF4 in the cerebellum.

Journal article

The devastating nature and lack of effective treatments associated with neurodegenerative diseases have stimulated a world-wide search for the elucidation of their molecular basis to which mouse models have made a major contribution. In combination with transgenic and knockout technologies, large-scale mouse mutagenesis is a powerful approach for the identification of new genes and associated signalling pathways controlling neuronal cell death and survival. Here we review the characterization...

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Authors: Bitoun, E; Davies, K

• Publication status: Published
• Journal: Cerebellum (London, England)
• Volume: 4
• Issue: 4
• Pages: 250-260
• Publication date: 2005-01-01
• DOI: 10.1080/14734220500325897
• EISSN: 1473-4230
• ISSN: 1473-4222
• Language: English
• Keywords: Amino Acid Sequence; Humans; Molecular Sequence Data; Mice; Animals; Neurodegenerative Diseases; Disease Models, Animal; DNA-Binding Proteins; Mice, Mutant Strains; Cerebellum; Sequence Homology, Amino Acid; Nuclear Proteins