The effect of white matter low attenuation on cognitive performance in dementia of the Alzheimer type.

Journal article

The effect of leukoaraiosis or white matter low attenuation (WMLA) on cognitive function is not fully understood. We compared the neuropsychological performance of 37 Alzheimer's disease patients with WMLA on CT brain scans with a similar group of 31 Alzheimer's disease patients with no evidence of white matter lesions. Patients with WMLA performed significantly worse on tests of visuospatial function (Cube Analysis test, p = 0.004), and cognitive speed (Kenrick Digit Copying test, p = 0.05) ...

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Authors: Amar, K; Bucks, R; Lewis, T; Scott, M; Wilcock, G

• Publication status: Published
• Journal: Age and ageing
• Volume: 25
• Issue: 6
• Pages: 443-448
• Publication date: 1996-11-01
• DOI: 10.1093/ageing/25.6.443
• EISSN: 1468-2834
• ISSN: 0002-0729
• Language: English
• Keywords: Mental Recall; Neuropsychological Tests; Male; Reaction Time; Geriatric Assessment; Alzheimer Disease; Humans; Female; Tomography, X-Ray Computed; Cerebral Cortex; Attention; Aged, 80 and over; Aged; Pattern Recognition, Visual