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Markers of platelet activation and apoptosis during storage of apheresis- and buffy coat-derived platelet concentrates for 7 days.

Abstract:

BACKGROUND: The different production methods for platelet concentrates (PCs) result in products with variable in vitro quality and in vivo viability. The aim of this study was to compare in vitro variables of PCs produced by apheresis (AP-PC) or the buffy coat (BC-PC) method by applying a number of new and established assays. STUDY DESIGN AND METHODS: Standard TRIMA Accel (Gambro BCT) AP-PCs (n = 20) and BC-PCs (n = 20) were stored in 100 percent plasma and changes in mitochondrial membrane ...

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Publication status:
Published

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Journal:
Transfusion More from this journal
Volume:
49
Issue:
1
Pages:
108-117
Publication date:
2009-01-01
DOI:
EISSN:
1537-2995
ISSN:
0041-1132
Language:
English
Keywords:
Pubs id:
pubs:191184
UUID:
uuid:0bf8a679-f31f-4e4b-a771-56a5fb351f0e
Local pid:
pubs:191184
Source identifiers:
191184
Deposit date:
2013-11-16

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