Journal article
Doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure N-enoyl oxazolidin-2-ones: a mechanistic probe
- Abstract:
- The doubly diastereoselective conjugate addition of the antipodes of lithium N-benzyl-N-(α-methylbenzyl)amide to a range of enantiopure N-enoyl oxazolidin-2-ones has been used as a mechanistic probe to determine that the reactive conformation is the anti-s-cis form. The β-amino carbonyl products resulting from these conjugate addition reactions are useful templates for further elaboration into an α,β,α-pseudotripeptide. © 2010 Elsevier Ltd. All rights reserved.
- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.tetasy.2010.03.033
Authors
- Journal:
- TETRAHEDRON-ASYMMETRY More from this journal
- Volume:
- 21
- Issue:
- 13-14
- Pages:
- 1635-1648
- Publication date:
- 2010-07-14
- DOI:
- EISSN:
-
1362-511X
- ISSN:
-
0957-4166
- Language:
-
English
- Pubs id:
-
pubs:110644
- UUID:
-
uuid:0bf62b85-5b4c-41bf-920e-95d0b6f05186
- Local pid:
-
pubs:110644
- Source identifiers:
-
110644
- Deposit date:
-
2012-12-19
- ARK identifier:
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- Copyright date:
- 2010
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