Journal article

A highly enantioselective total synthesis of (+)-goniodiol.

Abstract:: A high-yielding enantioselective total synthesis of the bioactive styryllactone (+)-goniodiol has been realised, starting from readily available (S)-glycidol. A key step is an oxygen-to-carbon rearrangement of a silyl enol ether linked via an anomeric centre, facilitating the rapid and diastereoselective construction of this functionalised system.

Publication status:: Published

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APA Style

Tate, E., Dixon, D., & Ley, S. (2006). A highly enantioselective total synthesis of (+)-goniodiol. Organic and Biomolecular Chemistry, 4(9), 1698–1706.

MLA Style

Tate, E, et al. “A Highly Enantioselective Total Synthesis of (+)-Goniodiol.” Organic and Biomolecular Chemistry, vol. 4, no. 9, 2006, pp. 1698–706.

Chicago Style

Tate, E, D Dixon, and S Ley. 2006. “A Highly Enantioselective Total Synthesis of (+)-Goniodiol.” Organic and Biomolecular Chemistry 4 (9): 1698–1706.
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Publisher copy:: 10.1039/b602805e

Authors

+ Tate, E More by this author

Role:: Author

+ Dixon, D More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Ley, S More by this author

Role:: Author

Journal:: Organic and biomolecular chemistry More from this journal
Volume:: 4
Issue:: 9
Pages:: 1698-1706
Publication date:: 2006-05-01
DOI:: 10.1039/b602805e
EISSN:: 1477-0539
ISSN:: 1477-0520

Language:: English
Keywords:: Ether, Ethyl

Pyrones

Lactones

Propanols

Stereoisomerism

Epoxy Compounds
Pubs id:: pubs:52069
UUID:: uuid:0bdbe900-2d72-46ce-9290-f9f2f3bcfb69
Local pid:: pubs:52069
Source identifiers:: 52069
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_0bdbe9002d7246ce9290f9f2f3bcfb69

Terms of use

Copyright date:: 2006

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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