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Evaluation of acute and convalescent antibody concentration against pneumococcal capsular polysaccharides for the diagnosis of pneumococcal infection in children with community-acquired pneumonia

Abstract:
We evaluated whether the quantification of IgG to pneumococcal capsular polysaccharides is an accurate diagnostic test for pneumococcal infection in children with pneumonia in Nepal. Children with pneumococcal pneumonia did not have higher convalescent, or higher fold change, IgG to pneumococcal polysaccharides than children with other causes of pneumonia. Caution is needed in interpreting antibody responses in pneumococcal infections.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1097/INF.0000000000004185

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
ORCID:
0000-0003-3403-4746
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author

Contributors

Role:
Contributor


Publisher:
Wolters Kluwer
Journal:
Pediatric Infectious Disease Journal More from this journal
Volume:
43
Issue:
2
Pages:
e67-e70
Publication date:
2024-01-11
Acceptance date:
2023-10-23
DOI:
EISSN:
1532-0987
ISSN:
0891-3668


Language:
English
Keywords:
Pubs id:
1606229
Local pid:
pubs:1606229
Deposit date:
2024-01-31
ARK identifier:

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