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Incorporating chemical signalling factors into cell-based models of growing epithelial tissues

Abstract:

In this paper we present a comprehensive computational framework within which the effects of chemical signalling factors on growing epithelial tissues can be studied. The method incorporates a vertex-based cell model, in conjunction with a solver for the governing chemical equations. The vertex model provides a natural mesh for the finite element method (FEM), with node movements determined by force laws. The arbitrary Lagrangian–Eulerian formulation is adopted to account for domain movement ...

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Publisher:
Springer
Publication date:
2012-01-01
UUID:
uuid:0bbffa3d-cfdf-4d7f-a1cb-1076337e136f
Local pid:
oai:eprints.maths.ox.ac.uk:1598
Deposit date:
2012-09-06

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