Structure-function relationships of the extracellular domain of the autosomal dominant polycystic kidney disease-associated protein, polycystin-1.

Weston, BS; Malhas, AN; Price, RG

Abstract:

Polycystin-1 (PC-1) is a member of a novel family of proteins that have a multidomain structure. Although the C-terminal intracellular segments have been extensively studied, mainly with respect to their putative involvement in cell signalling, the potential function of the extracellular domains has received less attention. Mutations in PC-1 result in autosomal dominant polycystic kidney disease (ADPKD) which is characterised by perturbation of transport resulting in fluid accumulation, cell ...

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APA Style

Weston, B. S., Malhas, A. N., & Price, R. G. (2003). Structure-function relationships of the extracellular domain of the autosomal dominant polycystic kidney disease-associated protein, polycystin-1. FEBS Letters, 538(1-3), 8–13.

MLA Style

Weston, B. S., et al. “Structure-Function Relationships of the Extracellular Domain of the Autosomal Dominant Polycystic Kidney Disease-Associated Protein, Polycystin-1.” FEBS Letters, vol. 538, no. 1-3, FEBS letters, 2003, pp. 8–13.

Chicago Style

Weston, BS, AN Malhas, and RG Price. 2003. “Structure-Function Relationships of the Extracellular Domain of the Autosomal Dominant Polycystic Kidney Disease-Associated Protein, Polycystin-1.” FEBS Letters 538 (1-3): 8–13.
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