Journal article
Structure-function relationships of the extracellular domain of the autosomal dominant polycystic kidney disease-associated protein, polycystin-1.
- Abstract:
-
Polycystin-1 (PC-1) is a member of a novel family of proteins that have a multidomain structure. Although the C-terminal intracellular segments have been extensively studied, mainly with respect to their putative involvement in cell signalling, the potential function of the extracellular domains has received less attention. Mutations in PC-1 result in autosomal dominant polycystic kidney disease (ADPKD) which is characterised by perturbation of transport resulting in fluid accumulation, cell ...
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Bibliographic Details
- Journal:
- FEBS letters
- Volume:
- 538
- Issue:
- 1-3
- Pages:
- 8-13
- Publication date:
- 2003-03-01
- DOI:
- EISSN:
-
1873-3468
- ISSN:
-
0014-5793
- Source identifiers:
-
55794
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:55794
- UUID:
-
uuid:0bbd15bd-144a-425c-a62b-21f58d334e81
- Local pid:
- pubs:55794
- Deposit date:
- 2012-12-20
Terms of use
- Copyright date:
- 2003
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