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Brain 5-HT function in obsessive-compulsive disorder. Prolactin responses to d-fenfluramine.

Abstract:

BACKGROUND: Drugs that potentiate brain serotonin (5-HT) neurotransmission are effective in the treatment of obsessive-compulsive disorder (OCD), but it is unclear whether disturbances in brain 5-HT function play a role in the pathophysiology of OCD. METHOD: We studied the prolactin response to the selective 5-HT releasing agent d-fenfluramine in 14 non-depressed, drug-free OCD patients, and 14 healthy controls matched for age and gender. RESULTS: The prolactin response to d-fenfluramine was ...

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Publication status:
Published

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Publisher copy:
10.1192/bjp.171.3.280

Authors


Fineberg, NA More by this author
Roberts, A More by this author
Montgomery, SA More by this author
Journal:
The British journal of psychiatry : the journal of mental science
Volume:
171
Issue:
3
Pages:
280-282
Publication date:
1997-09-05
DOI:
EISSN:
1472-1465
ISSN:
0007-1250
URN:
uuid:0bade586-68b5-4537-99f9-e99f132c38cd
Source identifiers:
186050
Local pid:
pubs:186050

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