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Long-term homeostasis of extracellular glutamate in the rat cerebral cortex across sleep and waking states.

Abstract:

Neuronal firing patterns, neuromodulators, and cerebral metabolism change across sleep-waking states, and the synaptic release of glutamate is critically involved in these processes. Extrasynaptic glutamate can also affect neural function and may be neurotoxic, but whether and how extracellular glutamate is regulated across sleep-waking states is unclear. To assess the effect of behavioral state on extracellular glutamate at high temporal resolution, we recorded glutamate concentration in pre...

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Journal:
Journal of neuroscience : the official journal of the Society for Neuroscience More from this journal
Volume:
29
Issue:
3
Pages:
620-629
Publication date:
2009-01-01
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
Language:
English
Keywords:
Pubs id:
pubs:456112
UUID:
uuid:0b9d3774-ec89-4cae-b7c4-10aa8aa91b12
Local pid:
pubs:456112
Source identifiers:
456112
Deposit date:
2014-05-13

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