Journal article
BigFoot: Bayesian alignment and phylogenetic footprinting with MCMC
- Abstract:
-
Background: We have previously combined statistical alignment and phylogenetic footprinting to detect conserved functional elements without assuming a fixed alignment. Considering a probability-weighted distribution of alignments removes sensitivity to alignment errors, properly accommodates regions of alignment uncertainty, and increases the accuracy of functional element prediction. Our method utilized standard dynamic programming hidden markov model ...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Evolutionary Biology Journal website
- Volume:
- 9
- Article number:
- 217
- Publication date:
- 2009-08-28
- Acceptance date:
- 2009-08-28
- DOI:
- EISSN:
-
1471-2148
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:0b957328-0332-4655-9d03-f1cf456d18f9
- Local pid:
- pubs:102891
- Source identifiers:
-
102891
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Satija et al
- Copyright date:
- 2009
- Notes:
- © 2009 Satija et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record