Graphical models for genetic analyses

Journal article

This paper introduces graphical models as a natural environment in which to formulate and solve problems in genetics and related areas. Particular emphasis is given to the relationships among various local computation algorithms which have been developed within the hitherto mostly separate areas of graphical models and genetics. The potential of graphical models is explored and illustrated through a number of example applications where the genetic element is substantial or dominating.

Authors: Lauritzen, S; Sheehan, N

• Publication status: Published
• Journal: STATISTICAL SCIENCE
• Volume: 18
• Issue: 4
• Pages: 489-514
• Publication date: 2003-11-01
• DOI: 10.1214/ss/1081443232
• ISSN: 0883-4237
• Language: English
• Keywords: probability propagation; Bayesian network; local computation; linkage analysis; QTL analysis; forensic genetics; peeling