Journal article icon

Journal article

Evidence for a role for insulin and growth hormone in overnight regulation of 3-hydroxybutyrate in normal and diabetic adolescents.

Abstract:

OBJECTIVE: To determine the relative effects of growth hormone and insulin on ketogenesis during puberty. RESEARCH DESIGN AND METHODS: We studied overnight changes in plasma ketones--3-hydroxybutyrate and acetoacetate--in 35 normal and 26 IDDM adolescents at different stages of puberty. The diabetic adolescents either were on their normal insulin regimen or were studied during an overnight euglycemic clamp with or without suppression of endogenous growth hormone release. RESULTS: Total ketone...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.2337/diacare.16.7.1011

Authors


Harris, DA More by this author
Phillips, PE More by this author
Matthews, DR More by this author
Expand authors...
Journal:
Diabetes care
Volume:
16
Issue:
7
Pages:
1011-1018
Publication date:
1993-07-05
DOI:
EISSN:
1935-5548
ISSN:
0149-5992
URN:
uuid:0b6b611a-a0b3-43a1-95b8-92f237ef0041
Source identifiers:
72784
Local pid:
pubs:72784

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP