- Abstract:
-
The neurotransmitter 5-hydroxytryptamine (5-HT, serotonin) mediates important brain functions and contributes to the pathophysiology and successful drug treatment of many common psychiatric disorders, especially depression. It is established that a key mechanism involved in the control of 5-HT neurones is feedback inhibition by presynaptic 5-HT autoreceptors, which are located on 5-HT cell bodies and nerve terminals. However, recent experiments have discovered an unexpected complexity of 5-HT...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.tips.2007.10.009
-
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- Journal:
- Trends in pharmacological sciences
- Volume:
- 28
- Issue:
- 12
- Pages:
- 629-636
- Publication date:
- 2007-12-05
- DOI:
- EISSN:
-
1873-3735
- ISSN:
-
0165-6147
- URN:
-
uuid:0b675aca-688a-4a3b-9439-0c7628b717ff
- Source identifiers:
-
185291
- Local pid:
- pubs:185291
- Copyright date:
- 2007
Journal article
Important messages in the 'post': recent discoveries in 5-HT neurone feedback control.
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